Overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondria-derived peptide commonly utilised in laboratory research involving mitochondrial-encoded peptides, cellular signalling pathways, and experimental biological systems. MOTS-c is a 16-amino acid peptide encoded within mitochondrial DNA.
In controlled research environments, it is used as a model compound in studies involving mitochondrial-derived peptides, peptide structure, and signalling pathway analysis.
MOTS-c has been studied in preclinical and laboratory models for potential roles in:
Mitochondrial Function – Linked to improved cellular energy regulation and mitochondrial gene expression.
Metabolic Regulation – Investigated for its role in glucose metabolism and insulin sensitivity.
Cellular Stress Response – Examined in relation to AMPK pathway activation and oxidative balance.
Aging and Longevity Research – Studied for its potential involvement in metabolic resilience and age-related processes.
Chemical reference information: Molecular formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂; Molecular weight: 2174.6 g/mol; Sequence: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH. These reference identifiers describe the formulation; the batch-specific analytical record identifies the supplied material.
Reference conditions for unreconstituted research material are −20°C with moisture and direct light excluded. Use the storage instructions on the supplied batch record for the actual presentation, and record any change of physical state or storage conditions.
Where laboratory preparation is required, use an appropriate validated solvent and aseptic peptide-handling procedure. Solvent compatibility, final concentration, and post-preparation storage depend on the specific formulation and experimental protocol. The catalog strength is the compound amount, not the concentration of a prepared solution.
NORVEXA Bioscience batch documentation can be requested using the printed reference and lot number. Review identity, analytical purity, presentation, and handling specifications before including a material in a laboratory workflow.
MOTS-c 10 mg is offered as a NORVEXA research vial. The selected strength refers to the compound content of this vial reference. Request the matching batch record for identity, analytical specifications, and presentation details.
Handling and storage
Reference conditions for unreconstituted research material are −20°C with moisture and direct light excluded. Use the storage instructions on the supplied batch record for the actual presentation, and record any change of physical state or storage conditions.
Where laboratory preparation is required, use an appropriate validated solvent and aseptic peptide-handling procedure. Solvent compatibility, final concentration, and post-preparation storage depend on the specific formulation and experimental protocol. The catalog strength is the compound amount, not the concentration of a prepared solution.
NORVEXA Bioscience batch documentation can be requested using the printed reference and lot number. Review identity, analytical purity, presentation, and handling specifications before including a material in a laboratory workflow.